Evidence Library

Randomized Controlled Trials

Drakulovic

1999 Respiratory

In patients who are mechanically ventilated does the semi-recumbent position vs. supine position reduce clinically suspected pneumonia?

Dec pneumonia (clinical suspicion & micro confirmed). Stopped early. Poor inclusion crit

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

SCCOPE

1999 Steroids

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

SHOCK

1999 Cardiology

302

Does early PCI in patients with cardiogenic shock from MI improve 30 day mortality?

Population: Cardiogenic Shock
Intervention: Early angiogram
Control: Medical stabilisation
Primary Outcome: 30 day mortality

Sort

1999 Antibiotics and Infection

#N/A

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

TRICC

1999 Transfusion

838

In patients admitted to ICU does a restrictive vs. liberal blood transfusion strategy alter mortality?

Can reduce threshold to 7-9g/dL w/o A/E > less cost, PRBC, pot Cx Caution IHD

Population: Adult ICU Patients
Intervention: RBCs
Control: Not recorded
Primary Outcome: Not recorded

Meduri 1998

1998 Respiratory Steroids

Question not recorded

Population: ARDS
Intervention: Late Methylprednisolone
Control: Placebo
Primary Outcome: All-cause mortality

VA Status Co-Op Study

1998 Neurology

#N/A

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Bracken III (NASCIS)

1997 Steroids

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

CAST

1997 Anticoagulation

#N/A

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Besson 1995

1995 Haemostasis

#N/A

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Brochard 1995

1995 Respiratory

NIV > reduced mortality (thru dec intubation) - long MV & hospi stays (ext valid?)

Population: Not recorded
Intervention: NIV
Control: Not recorded
Primary Outcome: Not recorded

NINDS

1995 Anticoagulation

Question not recorded

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Brochard 1994

1994 Respiratory

109

Question not recorded

PSV less weaning failure & ICU/hosp LOS, shorter weaning time. No diff T-piece vs SIMV

Population: Not recorded
Intervention: Weaning Strategy
Control: Not recorded
Primary Outcome: Not recorded

RSBI

1991 Respiratory

100

Question not recorded

RSBI > 100 --> 95% fail extubation, RSVBI < 100 --> 80% weaning success

Population: Not recorded
Intervention: Weaning Strategy
Control: Not recorded
Primary Outcome: Not recorded

Bozette 1990

1990 Steroids

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Bracken II (NASCIS)

1990 Steroids

#N/A

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Temkin 1990

1990 Neurology

#N/A

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Pickard 1989

1989 Neurology

554

Question not recorded

Nimodipine 60mg Q4H-dec cerebral infarction & poor o/c at 3mnths

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Bone 1987

1987 Steroids

#N/A

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Bracken I (NASCIS)

1984 Steroids

#N/A

Population: Not recorded
Intervention: Not recorded
Control: Not recorded
Primary Outcome: Not recorded

Allen 1983

1983 Neurology

121

Nimodipine-dec mortality & neuro deficits due to vasospasm

Population: Subarachnoid Hemorrhage
Intervention: Nimodipine
Control: Placebo
Primary Outcome: Not recorded