In patients presenting with acute uncomplicated appendicitis, is antibiotic therapy non-inferior to appendicectomy surgery?
- Population
- Surgical Patients
- Intervention
- Antibiotics
- Control
- Appendicectomy
- Primary Outcome
- Not recorded
Evidence Library
Randomized Controlled Trials
In hypotensive patients with penetrating torso trauma, does a delayed fluid strategy, in comparison to an immediate fluid resuscitation strategy, lead to an improved survival?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In patients with cirrhosis and septic shock does terlipressin in comparison with noradrenaline improve haemodynamic parameters?
- Population
- Sepsis
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
#N/A
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
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- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
What is the clinical outcome of patients after major non-cardiac surgery in Europe?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In patients with cervical immobilisation, does the Mcgrath® videolaryngoscope compared to the Macintosh laryngoscope provide a better view of the larynx?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In adult patients with sepsis, severe sepsis or septic shock, is a single dose of etomidate for induction of anaesthesia, compared with any other induction, associated with a difference in …
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In older patients (over 80 years) admitted to Intensive Care Units, what factors are predictive of survival with good health-related quality of life?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In critically ill patients does early treatment with haloperidol decrease the time that survivors spend in delirium or coma?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
#N/A
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In critically ill adults, does a single induction dose of etomidate compared to ketamine affect organ failure scores during the subsequent first 3 days?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
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- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In patients undergoing elective laparoscopic cholecystectomy, does deep neuromuscular blockade permit the use of low-pressure pneumoperitoneum?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In patients with LVEF <35% undergoing cardiac surgery does levosimenden compared with placebo reduce the incidence of a composite outcome of: death at day 30; renal replacement therapy at day …
- Population
- Surgical Patients
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In patients who are administered vasopressor medication intravenously, what are the published reports on local tissue injury and extravasation?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In pre-hospital trauma patients undergoing rapid sequence intubation (RSI), does fentanyl-ketamine-rocuronium induction compared to etomidate-suxamethonium induction affect intubation success or haemodynamic responses to laryngoscopy?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In intensive care patients requiring orotracheal intubation, does video laryngoscopy (VL) compared to the Macintosh direct laryngoscope (DL) increase the frequency of first pass intubation?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In patients undergoing rapid sequence induction, does the use of suxamethonium or rocuronium (at a standard or higher dose), produce better intubating conditions?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
#N/A
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In high-risk patients undergoing gastrointestinal surgery, does a cardiac output-guided haemodynamic therapy algorithm compared to clinician-guided standard therapy reduce death and major morbidity within 30 days?
- Population
- Surgical Patients
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
Do observers of simulated family conversations discussing organ donation respond more favourably to the discussion if it contains extra information about the benefits of donation compared to a standard conversation?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
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- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
#N/A
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded
In adult Emergency Department patients requiring intravenous sedation for noxious procedures, does a combination of propofol and ketamine (ketofol), compared with single-agent propofol, cause fewer adverse respiratory events?
- Population
- Not recorded
- Intervention
- Not recorded
- Control
- Not recorded
- Primary Outcome
- Not recorded