EPaNIC
2011 Nutrition
7 ICUs
4640 patients
Early vs late parenteral nutrition (NRS => 3) -- 20% dextrose then TPN (from d3 vs d8)
Clinical Question
In critically ill adult patients, does late supplemental parenteral nutrition (PN), compared with early PN reduce the duration of dependency on intensive care?
Critical Appraisal
Key findings
Early PN > inc new infections, dur MV, hosp LOS, total healthcare cost
Critique
Non-blinded. Short ICU length of stay.
- Population
- Adult ICU Patients
- Population Details
- Not recorded
- Intervention Arms
-
Late parenteral nutrition
Started day 8 - Control Arms
-
Early parenteral nutrition
Started day 3 - Primary Outcome
- ICU length of stay
- Secondary Outcomes
- No difference in mortality , Decreased ICU LOS , Less mechanically ventilated days , Less new infections , Decreased duration of CRRT
- P Value
- 0.02
Outcome Results
Not recorded
Primary location: Belgium