EDEN
2012 Nutrition
44 ICUs
1000 patients
Trophic (10-20ml/hr) vs full enteral feeds in acute lung injury (w/i 48hrs ALI Dx)
Clinical Question
Initial trophic vs full enteral feeding in patients with acute lung injury
Critical Appraisal
Key findings
No diff vent-free days, 60d mort, organ-failure free days, ICU-free days, infection
- Population
- ARDS
- Population Details
- Not recorded
- Intervention Arms
-
Trophic enteric feeds (n=508)
6 days trophic (10 mL/hr) feeds - Control Arms
-
Full enteric feeds (n=492)
6 days full feeds - Primary Outcome
- Ventilator free days at day 28
- Secondary Outcomes
- No difference in mortality , No difference in ventilator free days , Less episodes of elevated gastric residual volumes
- P Value
- 0.89
Outcome Results
Not recorded
Primary location: USA
Landmark trial