?
Early PN
2013 Nutrition
? ICUs
1372 patients
Early PN (w/i 24hrs) in critically ill pts with relative contraindications to early EN
Clinical Question
In critically ill patients with relative contraindications to early enteral
nutrition (EN), does providing early parenteral nutrition (PN), improve
mortality?
Critical Appraisal
Key findings
No diff 60d mort or infection rates. Homogeneous usual care control, incl 40% PN
Critique
Non blinded. 40% of patients in control received PN
- Population
- Adult ICU Patients
- Population Details
- Not recorded
- Intervention Arms
-
Early PN with contraindications to EN
PN within 24 hours of admission - Control Arms
-
Standard Care
- Primary Outcome
- 60 day mortality
- Secondary Outcomes
- No difference in mortality , Less mechanically ventilated days , Improvement in RAND-36
- P Value
- 0.6
Outcome Results
Not recorded