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DahLIA
2016 Sedation and Delirium
? ICUs
74 patients
Dexmed (added to std care) for agitated delirium and duration mech ventilation
Clinical Question
Is Dexmedetomidone effective in reducing the incidence of agitated delirium and days on a ventilator?
Critical Appraisal
Key findings
Dec time to extubation, more rapid resolution delirium & sedation/analgesia sparing
Strengths
Patient centred primary outcome , Randomised , Clinical staff blinded , Multi-centre trial
Weaknesses
Underpowered
- Population
- Delirium
- Population Details
- Not recorded
- Intervention Arms
-
Dexmedetomidine between 0 and 1.5mcg/kg/hr
- Control Arms
-
Placebo
- Primary Outcome
- Ventilator free hours at 7 days
- Secondary Outcomes
- Not recorded
- P Value
- 0.01
Outcome Results
Not recorded