ABLE
2015 Transfusion
? ICUs
2430 patients
Transfusion: fresh (<8d-newest) vs standard (2-42d-oldest) age blood, effect on 90d mort
Clinical Question
In critically ill patients requiring blood, does transfusion with "fresh"
RBC's (stored for 8 days or less) compared with standard issue RBCs (stored
2-42 days) reduce 90 day mortality?
Critical Appraisal
Key findings
No diff in 90d mortality - incl subgroup analysis
- Population
- Not recorded
- Population Details
- Not recorded
- Intervention Arms
-
RBCs
‘Fresh’ blood transfusion – stored for 8 days or less - Control Arms
-
Standard Care
- Primary Outcome
- 90 day mortality
- Secondary Outcomes
- Not recorded
- P Value
- Not recorded
Outcome Results
Not recorded
Primary location: Canada
Landmark trial