SMART
2018 Fluids
? ICUs
14000 patients
Clinical Question
In critically ill patients does the administration of balanced crystalloids compared with saline, reduce a 30 day composite outcome of death, new renal replacement therapy or persistent renal dysfunction?
Critical Appraisal
Critique
The composite outcome ‘MAKE 30’ consisted of mortality, new renal-replacement therapy or persistent renal dysfunction
- Population
- Adult ICU Patients
- Population Details
- Not recorded
- Intervention Arms
-
Fluids
Balanced crystalloid - Control Arms
-
Normal Saline
- Primary Outcome
- Major Adverse Kidney Event at 30 days
- Secondary Outcomes
- Not recorded
- P Value
- 0.04
Outcome Results
Not recorded
Primary location: USA
Landmark trial