?
SAFE
2004 Fluids
? ICUs
6997 patients
Does fluid resuscitation with 4% albumin, compared to saline, affect mortality for patients in the ICU?
Clinical Question
Does fluid resuscitation with albumin, compared to saline, affect mortality
for patients in the ICU?
Critical Appraisal
Key findings
No mortality difference. Alb:N/S=1:1.4L. Alb safe. Post-hoc Alb worse TBI
Critique
Minimal weaknesses. Great trail.
- Population
- Adult ICU Patients
- Population Details
- Not recorded
- Intervention Arms
-
4% Albumin
4% Albumin - Control Arms
-
Normal Saline
- Primary Outcome
- Not recorded
- Secondary Outcomes
- No difference in mortality , Post-hoc: albumin had increased mortality in brain injury , Trends: sepsis worse with saline, trauma worse with albumin
- P Value
- Not recorded
Outcome Results
Not recorded