ROSE
2019 Respiratory
? ICUs
1006 patients
Clinical Question
In patients with moderate to severe ARDS, does a strategy of early
neuromuscular blockade with heavy sedation, as opposed to usual care with
lighter sedation targets, result in a lower 90 day mortality?
Critical Appraisal
Weaknesses
Stopped early
- Population
- ARDS
- Population Details
- Moderate to severe ARDS
- Intervention Arms
-
Cisatracurium + deep sedation
- Control Arms
-
Light sedation
- Primary Outcome
- 90 day mortality
- Secondary Outcomes
- Not recorded
- P Value
- 0.93
Outcome Results
Not recorded
Primary location: USA
Landmark trial