RESCUEicp
2016 Neurology
52 ICUs
408 patients
Decomp crani TBI & refrac IC HT vs med Mx+barb coma.Ab CTB,ICP> 25 (1-12h)
Clinical Question
In patients with a traumatic brain injury (TBI) and refractory intracranial hypertension, does decompressive craniectomy, result in more favourable mortality and neurological outcomes at 6 months, compared with barbiturate coma and continued medical management?
Critical Appraisal
Key findings
Crani > less mortality (6&12m), more PVS & disability-37% x-over med>crani
- Population
- Traumatic Brain Injury
- Population Details
- Not recorded
- Intervention Arms
-
Decompressive Craniectomy
- Control Arms
-
Medical therapy
- Primary Outcome
- Extended Glasgow Outcome Score
- Secondary Outcomes
- Not recorded
- P Value
- 0.01
Outcome Results
Not recorded
Primary location: Worldwide
Landmark trial