RELIEF
2018 Fluids
47 ICUs
3000 patients
Clinical Question
In adult patients undergoing major elective abdominal surgery, does a restrictive fluid regimen compared with a liberal fluid regimen reduce complications and improved disability-free survival?
Critical Appraisal
Critique
the hypothesis lacks biological plausibility
- Population
- Surgical Patients
- Population Details
- Risk of post operative complications
- Intervention Arms
-
Restrictive fluids
CSL bolus up to 5ml/kg,
then 5ml/kg/hr for surgery,
then 0.8ml/kg/hr for 24hrs - Control Arms
-
Liberal fluids
CSL bolus 10ml/kg,
then 8ml/kg/hr for surgery,
then 1.5ml/kg/hr for 24hrs - Primary Outcome
- Survival at 1 year
- Secondary Outcomes
- More AKI , More CRRT
- P Value
- 0.61
Outcome Results
Not recorded
Primary location: Worldwide