Ki
PermiT
2015 Nutrition
? ICUs
894 patients
Permissive underfeeding (40-60 vs 70-100%) in crit ill adults (non-prot calories) - 90d mort
Clinical Question
In critically ill adults, does restriction of non-protein calories
(permissive underfeeding) compared to standard feeding reduce mortality at
90 days?
Critical Appraisal
Key findings
Safe. No survival benefit. Small benefit poss but study too small
Critique
Lack of blinding. Only powered to detect a moderate survival benefit
- Population
- Adult ICU Patients
- Population Details
- Not recorded
- Intervention Arms
-
Permissive underfeeding
Caloric goal 40-60% of requirement, maintain protein requirement - Control Arms
-
Standard feed
- Primary Outcome
- 90 day mortality
- Secondary Outcomes
- No difference in mortality , No difference in any secondary outcome
- P Value
- 0.58
Outcome Results
Not recorded