?
OXYGEN-ICU
2016 Respiratory
? ICUs
434 patients
Conservative (94-98%) vs liberal (97-100%, upto PaO2 150) oxygen therapy in ICU pts
Clinical Question
In critically ill adults, does conservative oxygen therapy compared to liberal oxygen therapy reduce mortality?
Critical Appraisal
Key findings
Sig mort benefit, less shock, liver failure, bacteraemia (stopped early-earthquake)
Critique
Single centre, non-blinded, low fragility index
- Population
- Adult ICU Patients
- Population Details
- >72 hours in ICU
- Intervention Arms
-
Oxygen
Target SpO2 94%-98% - Control Arms
-
Standard oxygen therapy
- Primary Outcome
- ICU mortality
- Secondary Outcomes
- Not recorded
- P Value
- 0.01
Outcome Results
Not recorded