Meduri 2007
2007 Respiratory Steroids
? ICUs
91 patients
Meduri protocol for early ARDS
Clinical Question
In patients with early ARDS, does continuous methylprednisolone compared to placebo reduce lung injury scores within 7 days?
Critical Appraisal
Weaknesses
Baseline difference between groups
Critique
Poor methodology. Should not change practice based on this trial alone.
- Population
- ARDS
- Population Details
- Early ARDS
- Intervention Arms
-
Methylprednisolone infusion
Methylprednisolone infusion for 28 days - Control Arms
-
Placebo
- Primary Outcome
- Reduce lung injury scores
- Secondary Outcomes
- Not recorded
- P Value
- 0.01
Outcome Results
Not recorded
Primary location: USA