?
ICU-ROX
2019 Respiratory
? ICUs
965 patients
Clinical Question
In mechanically ventilated ICU patients does a conservative use of oxygen therapy compared to usual oxygen therapy affect the number of ventilator-free-days?
Critical Appraisal
Key findings
Subgroups:
Ischaemic hypoxic encephalopathy - better with conservative
Sepsis - better with usual care
Acute brain pathologies - better with usual care
Critique
Clinicians were unblinded. This may bias the attending physician to make decisions regarding management that impacts the outcome, particularly the decision to extubate the patient.
- Population
- Adult ICU Patients
- Population Details
- Requiring mechanical ventilation
- Intervention Arms
-
Oxygen
Sats 91 - 96% - Control Arms
-
Standard Care
- Primary Outcome
- Ventilator free days at day 28
- Secondary Outcomes
- No difference in mortality , No difference in neurological outcome
- P Value
- 0.9
Outcome Results
Not recorded