Hernandez
2016 Respiratory
? ICUs
527 patients
HFNC for 24hrs post extubation in patients at risk of re-intubation, non-inferior to NIV
Clinical Question
In critically ill patients who are at high risk for re-intubation, is high flow nasal oxygen non-inferior to non-invasive ventilation in reducing re-intubation and post-extubation respiratory failure?
Critical Appraisal
Key findings
HFNC > dec reintubation rates. No diff mortality. Frag Index 5. Baseline differences
Critique
Non-blinded with subjective definition of respiratory failure. Two primary outcomes.
- Population
- Adult ICU Patients
- Population Details
- At least 1 risk for re-intubation
- Intervention Arms
-
Nasal High Flow
High-flow nasal oxygen - Control Arms
-
NIV
- Primary Outcome
- Re-intubation within 72 hours
- Secondary Outcomes
- Not recorded
- P Value
- Not recorded
Outcome Results
Not recorded
Primary location: Spain