HARP2
2014 Respiratory
? ICUs
540 patients
ARDS & simvastatin (80mg daily for upto 28d) > effect on MV duration
Clinical Question
In mechanically ventilated adults with acute respiratory distress syndrome
(ARDS), does simvastatin compared to placebo reduce ventilator dependence?
Critical Appraisal
Key findings
No diff in vent free days, 28d mort, oygenation.Statins > more biochem A/E ,not serious
- Population
- ARDS
- Population Details
- Not recorded
- Intervention Arms
-
Simvastatin
- Control Arms
- Not recorded
- Primary Outcome
- Not recorded
- Secondary Outcomes
- Not recorded
- P Value
- Not recorded
Outcome Results
Not recorded
Primary location: UK