HACA
2000 Cardiac Arrest
? ICUs
275 patients
OOHCA: VF arrest, mild hypothermia vs normothermia (quick resus, ROSC w/i 1hr)
Clinical Question
In adults who suffer cardiac arrest due to ventricular fibrillation, does
mild hypothermia compared with standard normothermia improve neurological
outcome at 6 months?
Critical Appraisal
Key findings
Improved mortality & neuro (6m) with 32-34 deg, only 8% screened included
Critique
Quick resus
- Population
- Cardiac Arrest
- Population Details
- VF/pVT Arrest
- Intervention Arms
-
32–34°C for 24h
32–34°C for 24h - Control Arms
-
No temperature management
- Primary Outcome
- Neurological Outcome
- Secondary Outcomes
- Not recorded
- P Value
- 0.01
Outcome Results
Not recorded
Primary location: Europe
Landmark trial