Ferrer
2006 Respiratory
? ICUs
162 patients
Preventive NIV 24hrs vs normal O2 in high risk failure post extubation, passed SBT
Clinical Question
In patients with severe sepsis or septic shock, is the timing of first
administration of antibiotics associated with the in-hospital mortality
rate?
Critical Appraisal
Key findings
Decreased resp failure & ICU mortality. 90d mortality benefit in hypercapnia only
- Population
- Adult ICU Patients
- Population Details
- At least 1 risk for re-intubation
- Intervention Arms
-
NIV
- Control Arms
-
Standard Care
- Primary Outcome
- Re-intubation within 72 hours
- Secondary Outcomes
- Not recorded
- P Value
- 0.03
Outcome Results
Not recorded
Primary location: Spain
Landmark trial