Eurotherm3235
2015 Trauma
? ICUs
376 patients
Hypothermia (32-35 deg) for intracranial hypertension after TBI (+ICP > 20 )
Clinical Question
In patients with traumatic brain injury (TBI), does hypothermia (32-35°C) and standard care compared to standard care alone reduce death and major disability at 6 months after injury?
Critical Appraisal
Key findings
Therapeutic hypoT > increase mortality, worse neuro o/c. Fargility index 3
- Population
- Traumatic Brain Injury
- Population Details
- Not recorded
- Intervention Arms
-
Hypothermia
- Control Arms
- Not recorded
- Primary Outcome
- Extended Glasgow Outcome Score
- Secondary Outcomes
- Not recorded
- P Value
- 0.04
Outcome Results
Not recorded
Primary location: Europe
Landmark trial